Flunarizine reduces cerebral infarct size after photochemically induced thrombosis in spontaneously hypertensive rats.
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Flunarizine reduces cerebral infarct size after photochemically induced thrombosis in spontaneously hypertensive rats.
The cerebroprotective effect of flunarizine was studied in a minimally invasive model of photochemically induced cerebral infarction in spontaneously hypertensive rats. Intravenous administration of the photosensitizing dye rose bengal and intense focal illumination of the brain produced a deep cortical infarction that resulted from singlet oxygen-induced peroxidative injury to the endothelial ...
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Copyright: ß 2014 The PLOS ONE Staff. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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ژورنال
عنوان ژورنال: Stroke
سال: 1987
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.18.6.1113